Core Nutritionals - Core Hard Extreme Pineapple Strawberry
- KSM-66® - Reduction in cortisol levels
- DIM - Regulate healthy estrogen production
- L-Theanine - Increased measures of well being
- 2 extra ingredients: White Button Mushroom Extract and Pomegranate Extract
Core HARD is a Cortisol/Estrogen control supplement aimed at aiding you in losing that last bit of stubborn body fat. A powerful mix of adaptogens and mood elevating ingredients, The ingredients in HARD have been specifically chosen to balance your hormonal environment and maximize your lean mass.
Pomegranate Extract (Punica granatum) (hull) (ellagic acid 40%)
Pomegranate is a fruit-bearing deciduous shrub, endemic to and cultivated in wide swaths of both Europe and Asia. Pomegranate is also the predominant member of two species comprising the Punicaceae family
Pomegranate fruit has long been consumed as a dietary staple, and recent research has uncovered that the peel, in particular, harbors a broad range of physiologically active compounds known as polyphenols – most prominently ellagitannins. When consumed, these ellagitannins are hydrolyzed to ellagic acid in the gut, and released into the blood, allowing ellagic acid to be widely distributed to many target tissues and organs.
While still preliminary, emerging animal and in vitro data on PME (pomegranate extract) suggests that both specific and whole plant extracts may exert interesting endocrine effects. In a study examining the effects of PME on cultured human cells, PME was shown to down-regulate estrogen-receptor gene expression, and inhibit binding – suggesting that PME may possess some anti-estrogenic effects, at least in vitro. In another study in rats, PME’s robust antioxidant profile was hypothesized to increase androgenic activity via reducing oxygen radicals in the testes.
Though PME lacks robust human data, the available literature suggests that this compound may possess some highly useful physiological effects.
White Button Mushroom Extract (Agaricus blazei) (fruit) (30% polysaccharides)
Agaricus blazei, known commonly by a plethora of names – including button mushroom, white button mushroom, table mushroom, and champignon mushroom – is a small, edible mushroom endemic to North America and Europe. The most commonly consumed mushroom on the planet, commercial production and consumption of white button mushroom has existed since at least the early 18th century, while indigenous oral records suggest the plant was consumed for centuries prior.
Recent medical research has discovered that white button mushroom is a rich source of biologically-active compounds, including ergothioneine, an antioxidant with particularly potent free radical scavenging activity. Similar research has found that white button mushrooms – along with other varieties – possess unsaturated fatty acids such as linoleic acid, linolenic acid, and conjugated linoleic acid that may exert inhibitory activity on human aromatase, a cytochrome-P450 complex responsible for the conversion of testosterone into estrogen.
In two separate studies by similar researchers, both rats and human cell lines were fed and/or incubated with various extract strengths and doses of white button mushroom extract. Both the animal experiments and “in-cell” aromatase assays demonstrated that WBME exerted powerful anti-aromatase effects, reducing total aromatase amounts and activity across all experimental conditions.
The most encouraging aspect of these studies is the servings of white button mushroom used in the experimental conditions: they are easily achievable through oral consumption, unlike many other plant-based, physiologically active compounds.
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